Securing intellectual property is the heart of a good commercialization strategy. Because your intellectual property strategy is impacted by everything upstream and downstream, it is a good bet that the you will spend significant time and money at this stage. By integrating upstream information, such as scientific data provided by contract research organizations (CROs) and contract manufacturing organizations (CMOs), into intellectual property strategies at the earliest stage, the potential for generating, for example, increased revenue stream from licenses and investors is enhanced. By integrating downstream information in your intellectual property strategy, for example information regarding your anticipated regulatory pathway, your intellectual property strategy is enhanced by staking out what you predict will be on the market. The diagram above illustrates the commercialization process which leverages collaborator feedback, business model information, and other data, to . Using this system enhances intellectual property strategy development by incorporating downstream legal and business considerations into a patent application. For example, a patent application drafted to anticipate a potential licensee's product development and marketing strategies may enhance the value of the issued patent. Similarly, a patent application drafted to anticipate a future governmental regulatory focus may enhance the value of the issued patent.